Volume 34, Issue 5, 2018


Stroke at the acute stage is a major cause of disability in adults, and is associated with dysfunction of brain networks. However, the mechanisms underlying the changes in brain connectivity in stroke are far from fully elucidated. In this issue, Liang et al. describe their investigation of brain metabolism and metabolic connectivity after middle cerebral artery occlusion (MCAO) in a rat model of ischemic stroke at the acute stage using 18F-fluorodeoxyglucose positron emission tomography. The cover image shows the metabolic connections in the MCAO rat brain. See pages 833-841. (Cover image provided by Dr. Binbin Nie).