Research advancement in immunopathogenesis of myasthenia gravis
The Second Xiangya Hospital of Central South University, Changsha 410011, China
Abstract
Myasthenia gravis (MG) is an autoimmune neuromuscular junction disease mediated by antibodies against the acetylcholine receptor (AChR). The etiology and immunopathogenesis of MG remain unclear. Recent research has shown the involvement of autoantibodies, lymphocytes, cytokines and chemokines, in the pathogenesis of MG. Systematic factors are also demonstrated, such as inheritance and endocrine. This review indicates the research development in immunopathogenesis of MG.
Keywords
myasthenia gravis; immunological pathogenesis
