Ultrastructural Evidence of Altered Dendritic Morphology in the Prefrontal Cortex of Alzheimer's Model Rats
Jinyue Guo1,2 · Jing Liu1
· Yanchao Zhang1,3 ·
Jiazheng Liu1
· Hao Zhai1,4 · Linlin Li1
· Hua Han1,3
2026,42(9):1941–1959 [
Abstract] [
SpringerLink]
Ca2+-Independent Exocytosis Favors Axonal Release through Enlarged Fusion Pores in Sensory Neurons
Rong Huang1,2 · Xingyu Du1
· Qihui Wu1,3 · Yuan Wang1
· Yuqi Hang1
· Xi Wu1
· Yiman Li1
· Jie Li1
·
Zhongjun Qiao1
· Yinglin Li1
· Lili Yin1
· Xiaoxuan Sun1
· Bing Liu1
· Feipeng Zhu1
· Quanfeng Zhang1
·
Changhe Wang2,4 · Zuying Chai1,5 · Zhuan Zhou1
2026,42(9):1960–1970 [
Abstract] [
SpringerLink]
A Comprehensive Study of AAV Tropism in the Marmoset Brain
Kailun Fang1,2 · Hailin Liu1
· Yuting Yao1,3 · Zhen Xu1
· Xinyu Liu1
· Canbin Feng1
·
Yuanhua Liu1,2,4 · Tong Li5
· Guannan Geng1,2,6 · Ruoxi Wu7
· Junhui Xia7
·
Fan Yang1,2 · Linyu Shi7
· Hui Yang1,2,5,7 · Neng Gong1,2,3
2026,42(9):1971–1980 [
Abstract] [
SpringerLink]
Distinct Role of Specialized Cutaneous Schwann Cell Network in Acute and Chronic Pain Sensation
Shan‑Xin Zhang1,2,3 · Jing Yang3,4 · Yao Lou1,5 ·
Song‑Cheng Xu1
· Ran Guo1,5 · Zhen‑Zhong Xu2,3,6
2026,42(9):1981–1994 [
Abstract] [
SpringerLink]
Engineered Alzheimer Organoids Validate the Link Between Intracellular and Soluble p-Tau Biomarkers and Highlight the Contribution of Astrocytic Tau
Ru Zhang1,5 · Xiaoxu Dong2
· Gang Pei1,3,4,5 ·
Shichao Huang1,5
2026,42(9):1995–2009 [
Abstract] [
SpringerLink]
Targeting Fgr-STAT3 Mediated Autophagy Inhibition in the Spinal Cord Alleviates Neuropathic Pain in Rats
Liqiong He1,2 · Yu Zhang3
· Chunguang Yang1,2 · Zhifeng Huang1
· Kailu Zou1
· Qingwei Deng1
· Jianxi Zhang1
·
Malijiang Mulati1
· Bei Sun1,2 · Qulian Guo1,2 · Changsheng Huang1,2
2026,42(9):2010–2024 [
Abstract] [
SpringerLink]
Visual Perception and Gamma Oscillations in Cat V1 are Dynamically Correlated in Contrast Sensitivity Functions
Zheng Ye1,2,3,4 · Jian Ding3
· Changning Cheng2
· Hao Yu3,6 · Fei Xu2
· Qingyan Sun2
·
Hongbin Yang1 · Tianmiao Hua2 · Hao Wang4,5
2026,42(9):2025–2041 [
Abstract] [
SpringerLink]
Task-Dependent Heart-Brain Interactions Regulate Human Self-Awareness
Musi Xie1,2,3 · Hang Wu1,4 · Han Bao1,2,3 · Yihui Zhang5
· Yueyao Liu6
·
Junrong Han1,4 · Xilin Zhang1,2,3 · Pengmin Qin1,2,3,7
2026,42(9):2042–2056 [
Abstract] [
SpringerLink]
Deep Brain Stimulation for Disorders of Consciousness: From Mesocircuit Mechanisms to Circuit-Guided Precision Neuromodulation
Di Zang1 · Keiko Hasuike3
· Zengxin Qi4
·
Yanbing Yu1 · Peng Gui2
2026,42(9):2057–2075 [
Abstract] [
SpringerLink]
Beyond the Wiring: White Matter as a Dynamic Regulator of Brain Function and Disease
Chenzhao He1
· Debao Wu1
· Ailian Du1
·
Liang Zhang1,2
2026,42(9):2076–2100 [
Abstract] [
SpringerLink]
Sleep Disorders in Neurodegenerative Diseases: Pathological Correlations and Underlying Mechanisms
Zihui Wang1,2 · Feifei He3 · Lingzhi Li1 · Wei Wang1 · Lisan Zhang1 ·
Jinsong Tang2 · Weidong Le1,3
2026,42(9):2101–2126 [
Abstract] [
SpringerLink]
Decode the Ubiquitinome in Parkinson’s Disease: From Pathological Aggregates to Targeted DUB Therapeutics
Xi Yu1
· Qinshuai Ni2
· Litong Han1
· Shenghan Zhang1
· Huamin Xu3 ·
Junxia Xie1 · Yingjuan Liu1
2026,42(9):2127–2150 [
Abstract] [
SpringerLink]
Real-Time Monitoring of Anaesthetic-Induced Change of Consciousness States Associated with Brain Biophoton Information Integration
Na Liu1,2 · Qiao Wei1,2 · Chengming Xia1,2 · Jinzhong Li1,2 · Chunli Qin1,2 ·
Yan Sun1,2 · Zhuo Wang3
· Hao Lei4
· Jiapei Dai1,2
2026,42(9):2151–2156 [
Abstract] [
SpringerLink]
A Genetically Defined Thalamic Circuit Encodes Social Touch
Shuyan Geng1,2 · Chuanyao Sun1,2 · Xing Liu1,2 · Zixu Zhang1,2 · Shengru Hu1,2 ·
Hao Jiang1,2 · Xiaoxia Xue1,2 · Tianxiang Xu1,2 · Wei Xie2 · Mingdao Mu1,2
2026,42(9):2157–2161 [
Abstract] [
SpringerLink]
Rethinking Alzheimer’s Origins: Antimicrobial Amyloid and Tau Point to Potential Upstream Immune Triggers
Yingjie Song1
· Yongshun Guo2 · Yi Wang1 ·
Jiawei Zhou2,3
2026,42(9):2162–2166 [
Abstract] [
SpringerLink]
The Roles of Tbx2 in Cochlear Development and Auditory Function
Xiang Li1 · Yurou Zhang1
· Zhenghong Bi1 ·
Renjie Chai1,2
2026,42(9):2167–2172 [
Abstract] [
SpringerLink]
TREM2-mediated Crosstalk in ALS: Microglial Fate Transition, Protein Aggregate Clearance, and Peripheral Nerve Repair
Xiaoqiu Shu1,2 · Jiahong Zeng2
· Kejing Zhang3
2026,42(9):2173–2178 [
Abstract] [
SpringerLink]
Correction to: Engineered Alzheimer Organoids Validate the Link Between Intracellular and Soluble p-Tau Biomarkers and Highlight the Contribution of Astrocytic Tau
Ru Zhang1,5 · Xiaoxu Dong2
· Gang Pei1,3,4,5 ·
Shichao Huang1,5
2026,42(9):2179–2180 [
Abstract] [
SpringerLink]
About the Cover
Deep brain stimulation (DBS) is emerging as a potential strategy for restoring arousal and functional communication in carefully selected patients with disorders of consciousness. Zang et al. integrate mesocircuit mechanisms, connectome-guided targeting, cognitive–motor dissociation, and adaptive neuromodulation to chart a path from experimental stimulation toward circuit-guided precision therapy. On the cover, a mist-shrouded pine forest forms the folds of the cerebral cortex, evoking a brain whose pathways of communication have become obscured after severe injury. At its center, paired luminous roots symbolize the central thalamus, while a warm beam of DBS light represents re-engagement of the anterior forebrain mesocircuit. Firefly-like signals trace a narrow route through the forest, representing renewed cortico-striato-thalamo-cortical communication. The solitary figure following this path embodies covert consciousness and the cautious possibility of re-emerging from silence into meaningful interaction. See pages 2057–2075. (Cover designed by Di Zang & Peng Gui)
