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(2019 CLARIVATE ANALYTICS)


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Volume 36, Issue. 1, January, 2020


Original Articles

Inhibition of Muscular Nociceptive Afferents via the Activation of Cutaneous Nociceptors in a Rat Model of Inflammatory Muscle Pain
Yehong Fang• Jie Zhu • Wanru Duan • Yikuan Xie • Chao Ma
2020, 36(1): 1-10   [ Abstract]   [ SpringerLink]   [PDF]

SCN9A Epileptic Encephalopathy Mutations Display a Gain-offunction Phenotype and Distinct Sensitivity to Oxcarbazepine
Shuzhang Zhang • Zhiping Zhang • Yuan Shen • Yudan Zhu• Kun Du • Jingkang Guo • Yonghua Ji • Jie Tao
2020, 36(1): 11-24   [ Abstract]   [ SpringerLink]   [PDF]

Regional Metabolic Patterns of Abnormal Postoperative Behavioral Performance in Aged Mice Assessed by 1 H-NMR Dynamic Mapping Method
Taotao Liu • Zhengqian Li • Jindan He • Ning Yang• Dengyang Han • Yue Li • Xuebi Tian • Huili Liu • Anne Manyande • Hongbing Xiang • Fuqiang Xu • Jie Wang • Xiangyang Guo
2020, 36(1): 25-38   [ Abstract]   [ SpringerLink]   [PDF]

Dependence of Generation of Hippocampal CA1 Slow Oscillations on Electrical Synapses
Yuan Xu • Feng-Yan Shen • Yu-Zhang Liu • Lidan Wang • Ying-Wei Wang • Zhiru Wang
2020, 36(1): 39-48   [ Abstract]   [ SpringerLink]   [PDF]

Distribution and Functional Characteristics of Voltage-Gated Sodium Channels in Immature Cochlear Hair Cells
You Zhou • Chenchen Xia • Manli Yin • Xueling Wang • Hao Wu • Yonghua Ji
2020, 36(1): 49-65   [ Abstract]   [ SpringerLink]   [PDF]

Reviews

Regulation of Circadian Genes by the MAPK Pathway: Implications for Rapid Antidepressant Action
Xin-Ling Wang • Kai Yuan • Wen Zhang • Su-Xia Li • George Fu Gao • Lin Lu
2020, 36(1): 66-76   [ Abstract]   [ SpringerLink]   [PDF]

Connections Between Insomnia and Cognitive Aging
Claire E. Sexton • Konstantina Sykara • Elissaios Karageorgiou • Jenny Zitser • Talita Rosa • Kristine Yaffe• Yue Leng
2020, 36(1): 77-84   [ Abstract]   [ SpringerLink]   [PDF]

Research Highlights

More than Scratching the Surface: Recent Progress in Brain Mechanisms Underlying Itch and Scratch
Xu Liu • Xiu-Hua Miao• Tong Liu
2020, 36(1): 85-88   [ Abstract]   [ SpringerLink]   [PDF]

Plasma Replacement Therapy for Alzheimer’s Disease
Xu-long Ding • Peng Lei
2020, 36(1): 89-90   [ Abstract]   [ SpringerLink]   [PDF]

Insight

Gut Microbiota and Short Chain Fatty Acids: Influence on the Autonomic Nervous System
Jessica Bruning • Andrew Chapp • Gregory A. Kaurala • Renjun Wang • Stephen Techtmann • Qing-Hui Chen
2020, 36(1): 91-95   [ Abstract]   [ SpringerLink]   [PDF]


Number 1 / January

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Rapid antidepressant therapy has been shown to be related to the circadian rhythm, but the specific molecular pathways have not been clarified. Accumulating evidence shows that the mitogen-activated protein kinase (MAPK) pathway is involved in the mechanism of action of antidepressants, and can simultaneously modulate the circadian system. Wang et al. propose that the MAPK pathway is a common route through which various rapid antidepressants regulate circadian genes. In the cover image, the rat in the depressive-like state (left) has a disturbed circadian rhythm. In contrast, when the circadian rhythm is normalized via the MAPK pathway (right), the rat rapidly returns to a relatively normal mood state. See pages 6676. (Cover image provided by Xin-Ling Wang).