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Volume 36, Issue. 8, August, 2020


Editorial

Visuospatial Memory Alteration in Alzheimer’s Disease
Sen Lin
2020, 36(8): 829-830   [ Abstract]   [ SpringerLink]   [PDF]

Original Articles

Impaired Parahippocampal Gyrus–Orbitofrontal Cortex Circuit Associated with Visuospatial Memory Deficit as a Potential Biomarker and Interventional Approach for Alzheimer Disease
Lin Zhu • Zan Wang• Zhanhong Du • Xinyang Qi • Hao Shu• Duan Liu • Fan Su • Qing Ye • Xuemei Liu • Zheng Zhou • Yongqiang Tang • Ru Song • Xiaobin Wang • Li Lin • Shijiang Li • Ying Han • Liping Wang • Zhijun Zhang
2020, 36(8): 831-844   [ Abstract]   [ SpringerLink]   [PDF]

Sirt1-ROS-TRAF6 Signaling-Induced Pyroptosis Contributes to Early Injury in Ischemic Mice
Weijie Yan • Wei Sun • Jiahui Fan • Haiqing Wang • Song Han • Junfa Li • Yanling Yin
2020, 36(8): 845-859   [ Abstract]   [ SpringerLink]   [PDF]

Prefrontal Nectin3 Reduction Mediates Adolescent Stress-Induced Deficits of Social Memory, Spatial Working Memory, and Dendritic Structure in Mice
Hong-Li Wang • Ji-Tao Li• Han Wang• Ya-Xin Sun • Rui Liu • Xiao-Dong Wang • Yun-Ai Su • Tian-Mei Si
2020, 36(8): 860-874   [ Abstract]   [ SpringerLink]   [PDF]

Blockade of HCN2 Channels Provides Neuroprotection Against Ischemic Injury via Accelerating Autophagic Degradation in Hippocampal Neurons
Cheng Chen • Li Liu • Ya-Qiao Shu• Ping Jing • Yun Lu • Xiao-Xue Zhang • Xian-Gang Zong • Lian-Jun Guo • Chang-Jun Li
2020, 36(8): 875-894   [ Abstract]   [ SpringerLink]   [PDF]

Neurocognitive Correlates of Statistical Learning of Orthographic–Semantic Connections in Chinese Adult Learners
Xiuhong Tong • Yi Wang • Shelley Xiuli Tong
2020, 36(8): 895-906   [ Abstract]   [ SpringerLink]   [PDF]

Responses of Primary Afferent Fibers to Acupuncture-Like Peripheral Stimulation at Different Frequencies: Characterization by Single-Unit Recording in Rats
Ran Huo • Song-Ping Han• Feng-Yu Liu • Xiao-Jing Shou • Ling-Yu Liu • Tian-Jia Song • Fu-Jun Zhai • Rong Zhang • Guo-Gang Xing • Ji-Sheng Han
2020, 36(8): 907-918   [ Abstract]   [ SpringerLink]   [PDF]

Neuronal Activity in the Cerebellum During the Sleep-Wakefulness Transition in Mice
Li-Bin Zhang • Jie Zhang• Meng-Jia Sun • Hao Chen • Jie Yan • Fen-Lan Luo • Zhong-Xiang Yao • Ya-Min Wu • Bo Hu
2020, 36(8): 919-931   [ Abstract]   [ SpringerLink]   [PDF]

Letters to the Editor

Neural Tract Degeneration Correlates with Functional Impairment in Patients with Anoxic Brain Injury: A Tract-based Spatial Statistics Study
Ji-Yun Park • Sung Ho Park • Jeong-Hee Yang • Han Do Lee • Jiho Lee • Ki-Hyun Byeon • Seo Young Park • Dongseok Yang
2020, 36(8): 932-936   [ Abstract]   [ SpringerLink]   [PDF]

Probing for Conditioned Hallucinations Through Neural Activation in a Ketamine Mouse Model of Schizophrenia
Jenny L. Wu • Rebecca P. Haberman • Michela Gallagher • Ming Teng Koh
2020, 36(8): 937-941   [ Abstract]   [ SpringerLink]   [PDF]

CSF Brain-Reactive Autoantibodies are Elevated in Patients with Viral Encephalitis
Zhong-Yuan Yu• Jian-Hong Wang • Wei-Wei Li • Ye-Ran Wang • Noralyn B. Man˜ucat-Tan• Jun Wang • Ju Wang • Gao-Yu Cui • Jie-Xiang Pan • Shui-Xian Zhang • Zu-Juan Liu• Liang Tan • Yu-Hui Liu
2020, 36(8): 942-946   [ Abstract]   [ SpringerLink]   [PDF]

Ghrelin Reduces A-Type Potassium Currents in Dopaminergic Nigral Neurons via the PLC/PKCd Pathway
Bao Xue • Chen Li • Xiaoli Chang • Hong Jiang • Limin Shi • Junxia Xie
2020, 36(8): 947-950   [ Abstract]   [ SpringerLink]   [PDF]

Research Highlights

TASK-3: New Target for Pain-Relief
Wen-Jing Ren • Henning Ulrich• Alexey Semyanov • Peter Illes • Yong Tang
2020, 36(8): 951-954   [ Abstract]   [ SpringerLink]   [PDF]

A Lower-Brainstem Structure Coordinates Acquisition of Negative Experience
Lei Li
2020, 36(8): 955-957   [ Abstract]   [ SpringerLink]   [PDF]


Number 8 / August

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Visuospatial malfunction is a common symptom in Alzheimer’s disease (AD). To understand how the nervous system controls the deficient visuospatial memory in AD, the underling neural circuit needs to be identified. In the cover image, the para-hippocampal gyrus (PHG) is connected with the orbitofrontal cortex (OFC) along with neuronal transmission and a 5XFAD mouse looking in the direction of its destination, suggesting that the PHG–OFC circuit explains the neuro-anatomical basis of visuospatial memory deficits in AD, thereby providing a potential predictor for its progression and a promising interventional approach for AD. See pages 831–844. (Cover image provided by Prof. Zhijun Zhang).