TRPV4 Regulates Soman-Induced Status Epilepticus and Secondary Brain Injury via NMDA Receptor and NLRP3 Inflammasome
Shuai Wang • Huanhuan He • Jianhai Long • Xin Sui • Jun Yang •
Guodong Lin • Qian Wang • Yongan Wang • Yuan Luo
2021,37(7):905-920 [
Abstract] [
SpringerLink]
[PDF]
CCL2/CCR2 Contributes to the Altered Excitatory-inhibitory Synaptic Balance in the Nucleus Accumbens Shell Following Peripheral Nerve Injury-induced Neuropathic Pain
Xiao-Bo Wu • Qian Zhu • Yong-Jing Gao
2021,37(7):921-933 [
Abstract] [
SpringerLink]
[PDF]
Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Modulate the Anesthetic Potency of Isoflurane in Mice
Shiyi Zhao • Rui Li • Huiming Li • Sa Wang • Xinxin Zhang • Dan Wang •
Juan Guo • Huihui Li • Ao Li • Tingting Tong • Haixing Zhong •
Qianzi Yang • Hailong Dong
2021,37(7):934-946 [
Abstract] [
SpringerLink]
[PDF]
Rac1 Signaling in Amygdala Astrocytes Regulates Fear Memory Acquisition and Retrieval
Xiao-Cen Fan • Chao-Nan Ma • Jia-Chen Song • Zhao-Hui Liao • Nan Huang • Xing Liu • Lan Ma
2021,37(7):947-958 [
Abstract] [
SpringerLink]
[PDF]
Distinct Characteristics of Odor-evoked Calcium and Electrophysiological Signals in Mitral/Tufted Cells in the Mouse Olfactory Bulb
Han Xu • Chi Geng • Xinzhong Hua • Penglai Liu • Jinshan Xu •
Anan Li
2021,37(7):959-972 [
Abstract] [
SpringerLink]
[PDF]
Dysregulated CRMP Mediates Circadian Deficits in a Drosophila Model of Fragile X Syndrome
Juan Zhao • Jin Xue • Tengfei Zhu • Hua He • Huaixing Kang •
Xuan Jiang • Wen Huang • Ranhui Duan
2021,37(7):973-984 [
Abstract] [
SpringerLink]
[PDF]
Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons
Xiaolei Song • Haotian Chen • Zicong Shang1 • Heng Du • Zhenmeiyu Li • Yan Wen • Guoping Liu • Dashi Qi • Yan You1 • Zhengang Yang • Zhuangzhi Zhang • Zhejun Xu
2021,37(7):985-998 [
Abstract] [
SpringerLink]
[PDF]
CRH Neurons in the Laterodorsal Tegmentum Mediate Acute Stress-induced Anxiety
Wenqi Tang • Danqing Zhou • Siyu Wang • Sijia Hao • Xiaomeng Wang •
Mohamed Helmy • Junming Zhu • Hao Wang
2021,37(7):999-1004 [
Abstract] [
SpringerLink]
[PDF]
Restricted Feeding Resets Endogenous Circadian Rhythm in Female Mice Under Constant Darkness
Yue Mei • Huajing Teng • Zhigang Li1 • Cheng Zeng • Yuanyuan Li •
Wei Song • Kaifan Zhang • Zhong Sheng Sun • Yan Wang
2021,37(7):1005-1009 [
Abstract] [
SpringerLink]
[PDF]
Recent Progress in Non-motor Features of Parkinson’s Disease with a Focus on Circadian Rhythm Dysregulation
Yufei Liu • Long Niu • Xinyao Liu • Cheng Cheng • Weidong Le
2021,37(7):1010-1024 [
Abstract] [
SpringerLink]
[PDF]
Comprehensive Management of Daily Living Activities, behavioral and Psychological Symptoms, and Cognitive Function in Patients with Alzheimer's Disease: A Chinese Consensus on Alzheimer's Disease
Jianjun Jia • Jun Xu • Jun Liu • Yongjun Wang • Yanjiang Wang •
Yunpeng Cao • Qihao Guo • Qiuming Qu • Cuibai Wei • Wenshi Wei •
Junjian Zhang • Enyan Yu
2021,37(7):1025-1038 [
Abstract] [
SpringerLink]
[PDF]
Oligodendroglial GABAergic Signaling: More Than Inhibition!
Xianshu Bai • Frank Kirchhoff • Anja Scheller
2021,37(7):1039-1050 [
Abstract] [
SpringerLink]
[PDF]
Structural, Functional, and Molecular Imaging of Autism Spectrum Disorder
Xiaoyi Li • Kai Zhang • Xiao He • Jinyun Zhou • Chentao Jin •
Lesang Shen • Yuanxue Gao • Mei Tian • Hong Zhang
2021,37(7):1051-1071 [
Abstract] [
SpringerLink]
[PDF]
Activated Natural Killer Cells Hit Neurogenesis in the Aging Brain
Angelica Cuapio • Hans-Gustaf Ljunggren
2021,37(7):1072-1074 [
Abstract] [
SpringerLink]
[PDF]
STING-ing Pain: How Can Pro-inflammatory Signaling Attenuate Pain?
Wolfgang Liedtke
2021,37(7):1075-1078 [
Abstract] [
SpringerLink]
[PDF]
The Parabrachial Nucleus as a Key Regulator of Neuropathic Pain
Zilong Wang • Zhen-Zhong Xu
2021,37(7):1079-1081 [
Abstract] [
SpringerLink]
[PDF]
Combination of Biomedical Techniques and Paradigms to Improve Prognostications for Disorders of Consciousness
Ming Song • Jianghong He • Yi Yang • Tianzi Jiang
2021,37(7):1082-1084 [
Abstract] [
SpringerLink]
[PDF]
Autologous Transplantation for Parkinson's Disease Patients: Feasibility and Challenge
Qi Zhang • Yanlin Wang • Yukai Wang • Han Liu • Huifang Sun • Zhuoya Wang • Changhe Shi •
Jing Yang • Yuming Xu
2021,37(7):1085-1086 [
Abstract] [
SpringerLink]
[PDF]
Breakthrough in Structural and Functional Dissection of the Hypothalamo-Neurohypophysial System
Ying Wang • Huamin Xu • Xia Zhang
2021,37(7):1087-1089 [
Abstract] [
SpringerLink]
[PDF]
Nerve agents are among the deadliest poisons known to man. In this issue, Wang et al. demonstrate the “dual-switch” function of TRPV4 in the treatment of nerve agent intoxication. TRPV4 is a key target of soman poisoning due to its modulation of NMDA-mediated excitotoxicity in the early stage of poisoning and NLRP3-medicated neuroinflammation in the late stage. As shown in this cover image, the brain is attacked by the nerve agent soman, and a defensive line formed by blocking TRPV4 and its downstream NMDAR and NLRP3 pathways can effectively protects the brain against the nerve agent. See pages 905–920. (Cover image designed by Shuai Wang).
