Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy
Xiaodan Zhang1 • Xue Wen1 • Ismael Al-Ramahi2,3 • Juan Botas2,3 • Boxun Lu1 • Yuhua Fu1
1 School of Life Sciences, Fudan University, Shanghai 200438, China
2 Department of Molecular and Human Genetics, Baylor College of Medicine, Houston 77030, USA
3 Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, Houston 77030, USA
Abstract
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