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Current Issue Table of Contents:15 February 2022 Volume 38, Issue. 2


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Volume 38, Issue 2., February 2022


Original Articles

Loss of O-GlcNAcylation on MeCP2 at Threonine 203 Leads to Neurodevelopmental Disorders
Juanxian Cheng1 • Zhe Zhao1 • Liping Chen1 • Ying Li1 • Ruijing Du1 • Yan Wu1 • Qian Zhu1 • Ming Fan1,3 • Xiaotao Duan4 • Haitao Wu1,2,3
2022, 38(2):113–134   [ Abstract]   [ SpringerLink]   [PDF]

Protein Kinase C Controls the Excitability of Cortical Pyramidal Neurons by Regulating Kv2.2 Channel Activity
Zhaoyang Li1 • Wenhao Dong1 • Xinyuan Zhang1 • Jun-Mei Lu1 • Yan-Ai Mei1 • Changlong Hu1
2022, 38(2):135–148   [ Abstract]   [ SpringerLink]   [PDF]

A Neural Circuit Mechanism Controlling Breathing by Leptin in the Nucleus Tractus Solitarii
Hongxiao Yu1 • Luo Shi1 • Jinting Chen2 • Shirui Jun1 • Yinchao Hao1 • Shuang Wang1 • Congrui Fu3 • Xiang Zhang1 • Haiyan Lu4 • Sheng Wang1,5 • Fang Yuan1,5
2022, 38(2):149–165   [ Abstract]   [ SpringerLink]   [PDF]

Oxygen Metabolism-induced Stress Response Underlies Heart–brain Interaction Governing Human Consciousness-breaking and Attention
Xiao-Juan Xue1 • Rui Su2 • Ze-Feng Li1 • Xiao-Ou Bu2 • Peng Dang2 • Si-Fang Yu1 • Zhi-Xin Wang2 • Dong-Mei Chen2 • Tong-Ao Zeng2 • Ming Liu1,2 • Hai-Lin Ma2 • De-Long Zhang1,2
2022, 38(2):166–180   [ Abstract]   [ SpringerLink]   [PDF]

Digoxin Ameliorates Glymphatic Transport and Cognitive Impairment in a Mouse Model of Chronic Cerebral Hypoperfusion
Jie Cao1 • Di Yao1 • Rong Li1,2 • Xuequn Guo1,3 • Jiahuan Hao1 • Minjie Xie1 • Jia Li1 • Dengji Pan1 • Xiang Luo1 • Zhiyuan Yu1 • Minghuan Wang1 • Wei Wang1,4
2022, 38(2):181–199   [ Abstract]   [ SpringerLink]   [PDF]

Letters to the Editor

Drosophila Larval Light-Avoidance is Negatively Regulated by Temperature Through Two Pairs of Central Brain Neurons
Jie Wang1,2 • Weiqiao Zhao2 • Qianhui Zhao1,2 • Jinrun Zhou1,2 • Xinhang Li1,2 • Yinhui He1,2 • Zhefeng Gong1,2,3
2022, 38(2):200–204   [ Abstract]   [ SpringerLink]   [PDF]

Attention Field Size Alters Patterns of Population Receptive Fields in the Early Visual Cortex
Bo Liu1,4 • Xiaochun Wang1,2,4 • Le Wang1,2 • Qiaojun Qu1 • Wei Zhang1 • Bin Wang3,4 • Jie Xiang3 • Ting Yan5 • Tianyi Yan6,7 • Hui Zhang1,2,4
2022, 38(2):205–208   [ Abstract]   [ SpringerLink]   [PDF]

Review

Revealing the Precise Role of Calretinin Neurons in Epilepsy: We Are on the Way
Yingbei Qi1 • Heming Cheng1,2 • Yi Wang1,2 • Zhong Chen1,2
2022, 38(2):209–222   [ Abstract]   [ SpringerLink]   [PDF]

Research Highlights

A Specific Peptide Vaccine Against IDH1(R132H) Glioma
Yuqian Huang1,2 • Yongjie Wang1,2 • Zhihui Huang1,2
2022, 38(2):223–225   [ Abstract]   [ SpringerLink]   [PDF]

Pathway Matters: Prefrontal Control of Negative Emotions via Distinct Downstream Regions
Junqiang Zheng1,2 • Na Liu1,2 • Han Xu1,2
2022, 38(2):226–228   [ Abstract]   [ SpringerLink]   [PDF]

A Breakthrough in Understanding the Rapid Antidepressant Effect of Ketamine Based on Structural AnalysisRui Duan1
Hongmei Liu1 • Xiaohui Wu1 • Jun Chen1,3 • Yiru Fang1,2,3
2022, 38(2):229-231   [ Abstract]   [ SpringerLink]   [PDF]

Microglial SIRPα Deletion Facilitates Synapse Loss in Preclinical Models of Neurodegeneration
Chongyun Wu1 • Luodan Yang2 • Hannah Youngblood3 • Timon Cheng-Yi Liu1 • Rui Duan1
2022, 38(2) 232-234   [ Abstract]   [ SpringerLink]   [PDF]


Volume 38, Issue. 2, February 2022

Cheng et al. demonstrate that MeCP2 (methyl CpG binding protein 2) is modified by O-GlcNAc (O-linked β-N-acetylglucosamine) at threonine 203 (T203), an etiologic site in Rett syndrome, and highlight the critical role of MeCP2 T203 O-GlcNAcylation in neuronal development and synaptic transmission. In this cover image, Aladdin's lamp is symbolizes MeCP2, and the angel with broken wings is reminiscent of a child with Rett syndrome. The flash as the hand touches the lamp represents the T203 site mutation on MeCP2. See pages 113134 (Cover designed by Dr. Hai-Tao Wu).