Estrogen Receptor-A in Medial Preoptic Area Contributes to Sex Difference of Mice in Response to Sevoflurane Anesthesia
Yunyun Zhang1 • Huiming Li1 • Xinxin Zhang1 • Sa Wang1 • Dan Wang1 •
Jiajia Wang1 • Tingting Tong1 • Zhen Zhang1 • Qianzi Yang1 • Hailong Dong1
2022, 38(7): 703-719 [
Abstract] [
SpringerLink]
[PDF]
Transcriptome Analysis of Schwann Cells at Various Stages of Myelination Implicates Chromatin Regulator Sin3A in Control of Myelination Identity
Bin Zhang1 • Wenfeng Su1 • Junxia Hu1 • Jinghui Xu1 • Parizat Askar1 •
Shuangxi Bao1 • Songlin Zhou1 • Gang Chen1 • Yun Gu1
2022, 38(7): 720-740 [
Abstract] [
SpringerLink]
[PDF]
Formation of the Looming-evoked Innate Defensive Response during Postnatal Development in Mice
Shanping Chen1,3 • Huiying Tan1,3 • Zhijie Wang1 • Yu-ting Tseng1 •
Xiaotao Li1,2 • Liping Wang1
2022, 38(7): 741-752 [
Abstract] [
SpringerLink]
[PDF]
Multiple Mild Stimulations Reduce Membrane Distribution of CX3CR1 Promoted by Annexin a1 in Microglia to Attenuate Excessive Dendritic Spine Pruning and Cognitive Deficits Caused by a Transient Isc...
Lu Zheng1,2,3 • Yi Wang1,2,3 • Bin Shao1,2,3 • Huijuan Zhou1,2,3 • Xing Li1,2,3 • Cai Zhang4,5 • Ning Sun1,2,3 • Jing Shi1,2,3
2022, 38(7): 753-768 [
Abstract] [
SpringerLink]
[PDF]
Prestin-Mediated Frequency Selectivity Does not Cover Ultrahigh Frequencies in Mice
Jie Li1,2 • Shuang Liu1,2 • Chenmeng Song1,2 • Tong Zhu1,2 • Zhikai Zhao1,2 •
Wenzhi Sun3,4 • Yi Wang1,2 • Lei Song5,6,7 • Wei Xiong1,2
2022, 38(7): 769-784 [
Abstract] [
SpringerLink]
[PDF]
Cross-Modal Interaction and Integration Through Stimulus-Specific Adaptation in the Thalamic Reticular Nucleus of Rats
Yumei Gong1,2,3 • Yuying Zhai1 • Xinyu Du1 • Peirun Song1,2 • Haoxuan Xu1,2 •
Qichen Zhang1,2 • Xiongjie Yu1,2,3
2022, 38(7): 785-795 [
Abstract] [
SpringerLink]
[PDF]
From Parametric Representation to Dynamical System: Shifting Views of the Motor Cortex in Motor Control
Tianwei Wang1,2,3 • Yun Chen1,2,3 • He Cui1,2,3
2022, 38(7): 796-808 [
Abstract] [
SpringerLink]
[PDF]
Factors Influencing Alzheimer’s Disease Risk: Whether and How They are Related to the APOE Genotype
Rong Zhang1 • Xiaojiao Xu1 • Hang Yu1 • Xiaolan Xu1 • Manli Wang1 • Weidong Le1
2022, 38(7): 809-819 [
Abstract] [
SpringerLink]
[PDF]
Induced Dopaminergic Neurons for Parkinson’s Disease Therapy: Targeting the Striatum or Midbrain/Substantia Nigra Pars Compacta?
Huadong Xu1 • Xu Cheng1 • Qian Song2,3 • Yuxin Yang1,4 • Changhe Wang1,2,3 •
Xinjiang Kang1,4
2022, 38(7): 820-824 [
Abstract] [
SpringerLink]
[PDF]
Expanding Views of Mitochondria in Parkinson’s Disease: Focusing on PINK1 and GBA1 Mutations
Yu Yuan1 • Xizhen Ma1 • Ning Song1 • Junxia Xie1
2022, 38(7): 825-828 [
Abstract] [
SpringerLink]
[PDF]
The Mechanism for Allocating Limited Working Memory Resources in Multitasking
Lu Gan1 • Jinglong Wu1 • Ji Dai2,3,4 • Shintaro Funahashi1
2022, 38(7): 829-833 [
Abstract] [
SpringerLink]
[PDF]
Getting a Sense of ATP in Real Time
Anthony D. Umpierre1 • Koichiro Haruwaka1 • Long-Jun Wu1,2,3
2022, 38(7): 834-836 [
Abstract] [
SpringerLink]
[PDF]
Fundamental Neurocircuit of Anti-inflammatory Effect by Electroacupuncture Stimulation Identified
Jiayu Hu1,2,3 • Wanye Hu1,2,3 • Lusheng Tang3 • Ying Wang2
2022, 38(7): 837-839 [
Abstract] [
SpringerLink]
[PDF]
Sex differences in response to general anesthesia have been reported previously, but the underlying neural mechanism remained unknown. In the current study, male mice were confirmed to be more sensitive to sevoflurane than females. This sex difference was mediated by estrogen receptor α (ERα) on GABAergic neurons in the medical preoptic area (MPA) of males. ERα signaling stimulated the GABAergic MPA neurons in males but had no effect on that in females. The activation of GABAergic neurons exerted an inhibitory effect on neural networks that, in turn, facilitated the anesthesia process. In the cover image, the female mouse is fighting against sevoflurane anesthesia, while the male mouse has already fallen asleep. In the brain, ERα has ignited the MPA GABAergic neurons in the male mouse, but in the female, the GABAergic neurons keep silent. See pages 703–719. (Cover provided by Dr. Hailong Dong)
