KIF17 Modulates Epileptic Seizures and Membrane Expression of the NMDA Receptor Subunit NR2B
Yan Liu1 • Xin Tian1 • Pingyang Ke1 • Juan Gu1 • Yuanlin Ma1 • Yi Guo1 •
Xin Xu1 • Yuanyuan Chen1 • Min Yang1 • Xuefeng Wang1 • Fei Xiao
2022, 38(8):841–856 [
Abstract] [
SpringerLink]
[PDF]
AD-16 Protects Against Hypoxic-Ischemic Brain Injury by Inhibiting Neuroinflammation
Zhihua Huang1,2 • Zhengwei Luo1,2 • Andrea Ovcjak1 • Jiangfan Wan1,2 • Nai-hong Chen3 • Wenhui Hu4 • Hong-Shuo Sun1,2,5 • Zhong-Ping Feng1
2022, 38(8):857–870 [
Abstract] [
SpringerLink]
[PDF]
Intestinal Dopamine Receptor D2 is Required for Neuroprotection Against 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Dopaminergic Neurodegeneration
Hairong Peng1,2 • Shui Yu1,2 • Yukai Zhang1,2 • Yanqing Yin1 • Jiawei Zhou1,2,3
2022, 38(8):871–886 [
Abstract] [
SpringerLink]
[PDF]
Homocysteine-Induced Disturbances in DNA Methylation Contribute to Development of Stress-Associated Cognitive Decline in Rats
Shi-Da Wang1 • Xue Wang1 • Yun Zhao1 • Bing-Hua Xue1 • Xiao-Tian Wang1 •
Yu-Xin Chen1 • Zi-Qian Zhang1,2 • Ying-Rui Tian1,3 • Fang Xie1 • Ling-Jia Qian1
2022, 38(8):887–900 [
Abstract] [
SpringerLink]
[PDF]
P2X7/P2X4 Receptors Mediate Proliferation and Migration of Retinal Microglia in Experimental Glaucoma in Mice
Meng-Xi Xu1 • Guo-Li Zhao1 • Xin Hu1 • Han Zhou1 • Shu-Ying Li1 •
Fang Li1 • Yanying Miao1 • Bo Lei2 • Zhongfeng Wang1
2022, 38(8):901–915 [
Abstract] [
SpringerLink]
[PDF]
A Critical Role for γCaMKII in Decoding NMDA Signaling to Regulate AMPA Receptors in Putative Inhibitory Interneurons
Xingzhi He1,2 • Yang Wang1,2 • Guangjun Zhou1,2 • Jing Yang1,2 • Jiarui Li1,2 •
Tao Li1,2 • Hailan Hu1,2,3 • Huan Ma1,2,3
2022, 38(8):916–926 [
Abstract] [
SpringerLink]
[PDF]
Differential Kinematic Encoding of Saccades and Smooth-pursuit Eye Movements by Fastigial Neurons
Zongpeng Sun1 • Peter W. Dicke2 • Peter Thier2
2022, 38(8):927–932 [
Abstract] [
SpringerLink]
[PDF]
Transcription Factor MAFA Regulates Mechanical Sensation by Modulating Piezo2 Expression
Chang-ming Wang1 • Dustin P. Green2 • Xinzhong Dong3,4,5,6
2022, 38(8):933–937 [
Abstract] [
SpringerLink]
[PDF]
Correlation of Ferroptosis and Other Types of Cell Death in Neurodegenerative Diseases
Xiaoting Dang1 • Xuejie Huan1 • Xixun Du1 • Xi Chen1 • Mingxia Bi1 •
Chunling Yan1 • Qian Jiao1 • Hong Jiang1
2022, 38(8):938–952 [
Abstract] [
SpringerLink]
[PDF]
Astrocytes in Post-traumatic Stress Disorder
Baoman Li1 • Dianjun Zhang1 • Alexei Verkhratsky1,2,3
2022, 38(8):953–965 [
Abstract] [
SpringerLink]
[PDF]
Can You Feel the Love Tonight: A Dipeptidergic Circuit for Pleasant Touch
Jing-Jing Yan1 • Wen Zhang1 • Xiao-Hong Xu1
2022, 38(8):966–968 [
Abstract] [
SpringerLink]
[PDF]
Combining Multiple Factors to Predict Alzheimer’s Disease
Xiao-Lin Gao1,2 • Jun Wang1,2 • Yan-Jiang Wang1,2,3,4,5 • Xian-Le Bu1,2,3
2022, 38(8):969–972 [
Abstract] [
SpringerLink]
[PDF]
Time to Reconsider Routine Timely Anti-epileptic Medication: Raising Hope with a “Smart” Nanoengineered System
Yingying Tang1 • Jianan Quan1 • Weijie Zhou1 • Haoliang Zhou1
2022, 38(8):973–975 [
Abstract] [
SpringerLink]
[PDF]
Targeting the Cuneiform Nucleus in Parkinson’s Disease: Option to Improve Locomotor Activity
Wei Cui1 • Bao Xue1 • Junxia Xie2 • Huamin Xu1,2
2022, 38(8):976–978 [
Abstract] [
SpringerLink]
[PDF]
Kinesin superfamily motor protein 17 (KIF17) transports N-methyl-D-aspartate receptor subtype 2B (NR2B) from the neuronal cytoplasm to the dendrites under physiological conditions to maintain the balance between neuronal excitation and inhibition. In this issue, Liu et al. report that in epilepsy, excess KIF17 drives the abnormal enhancement of this process. The cover image is derived from the Chinese mythology “The Mythical Bird Jingwei Trying to Fill up the Sea with Pebbles” (精卫填海), which is usually used to describe people who are firm and indomitable and will not stop until they reach their goal. KIF17 is like the Jingwei bird. Excess KIF17 activity results in excessive transport of the NR2B subunit in the neuronal cytoplasm to the postsynaptic membrane, leading to altered susceptibility to epilepsy. See pages 841–856 (cover provided by Drs Yan Liu and Xin Tian).
