Disrupted Maturation of Prefrontal Layer 5 Neuronal Circuits in an Alzheimer’s Mouse Model of Amyloid Deposition
Chang Chen1,2 · Jing Wei2
· Xiaokuang Ma2
· Baomei Xia2
· Neha Shakir2
· Jessica K. Zhang2
· Le Zhang2
·
Yuehua Cui2
· Deveroux Ferguson2
· Shenfeng Qiu2
· Feng Bai1
2023,39(6):881–892 [
Abstract] [
SpringerLink]
[PDF]
Noninvasive Tracking of Every Individual in Unmarked Mouse Groups Using Multi-Camera Fusion and Deep Learning
Feng Su1,2,3,4 · Yangzhen Wang5
· Mengping Wei1
· Chong Wang6
· Shaoli Wang7
·
Lei Yang1
· Jianmin Li8
· Peijiang Yuan9
· Dong‑Gen Luo4
· Chen Zhang1,2,3
2023,39(6):893–910 [
Abstract] [
SpringerLink]
[PDF]
Leaky Gut Plays a Critical Role in the Pathophysiology of Autism in Mice by Activating the Lipopolysaccharide-Mediated Toll-Like Receptor 4–Myeloid Differentiation Factor 88–Nuclear Factor Kapp...
Fang Li1
· Haoran Ke2
· Siqi Wang3
· Wei Mao1
· Cexiong Fu4
· Xi Chen5
·
Qingqing Fu6
· Xiaori Qin1
· Yonghua Huang1
· Bidan Li4
· Shibing Li7
·
Jingying Xing8
· Minhui Wang9
· Wenlin Deng10
2023,39(6):911–928 [
Abstract] [
SpringerLink]
[PDF]
REEP1 Preserves Motor Function in SOD1G93A Mice by Improving Mitochondrial Function via Interaction with NDUFA4
Siyue Qin1
· Pan You1
· Hui Yu1
· Bo Su1
2023,39(6):929–946 [
Abstract] [
SpringerLink]
[PDF]
CircFhit Modulates GABAergic Synaptic Transmission via Regulating the Parental Gene Fhit Expression in the Spinal Dorsal Horn in a Rat Model of Neuropathic Pain
Ting Xu1,2 · Zhen‑Yu Li1,2 · Meng Liu3
· Su‑Bo Zhang1
· Huan‑Huan Ding4
· Jia‑Yan Wu1,2 · Su‑Yan Lin5 ·
Jun Liu5
· Jia‑You Wei1,6 · Xue‑Qin Zhang7
· Wen‑Jun Xin1,2,8
2023,39(6):947–961 [
Abstract] [
SpringerLink]
[PDF]
Corticostriatal Neurons in the Anterior Auditory Field Regulate Frequency Discrimination Behavior
Zhao‑Qun Wang1 · Hui‑Zhong Wen1 · Tian‑Tian Luo1 · Peng‑Hui Chen1 · Yan‑Dong Zhao1 · Guang‑Yan Wu2 · Ying Xiong1
2023,39(6):962–972 [
Abstract] [
SpringerLink]
[PDF]
The Emotion-Regulation Benefits of Implicit Reappraisal in Clinical Depression: Behavioral and Electrophysiological Evidence
Jiajin Yuan1 · Yueyao Zhang2 · Yanli Zhao3 · Kexiang Gao2 · Shuping Tan3 · Dandan Zhang1,4,5
2023,39(6):973–983 [
Abstract] [
SpringerLink]
[PDF]
Different Regional Patterns in Gray Matter-based Age Prediction
Nianming Zuo1,2,3,4 · Tianyu Hu1,2,3 · Hao Liu1,2,3 ·
Jing Sui1,2,3,5 · Yong Liu1,2,3,5 · Tianzi Jiang1,2,3,4,5,6,7
2023,39(6):984–988 [
Abstract] [
SpringerLink]
[PDF]
TRPM7 Kinase Domain is Part of the Rac1-SSH2-cofilin Complex Regulating F-actin in the Mouse Nervous System
Junzhuang Chang1
· Cui Chen1
· Wei Li1
·
Nashat Abumaria
2023,39(6):989–993 [
Abstract] [
SpringerLink]
[PDF]
Neural Circuit Mechanisms Involved in Animals’ Detection of and Response to Visual Threats
Qiwen Wu1,2 · Yifeng Zhang1
2023,39(6):994–1008 [
Abstract] [
SpringerLink]
[PDF]
Hippocampus: Molecular, Cellular, and Circuit Features in Anxiety
Hu‑Jiang Shi1
· Shuang Wang1
· Xin‑Ping Wang1
·
Rui‑Xin Zhang1
· Li‑Juan Zhu1,2
2023,39(6):1009–1026 [
Abstract] [
SpringerLink]
[PDF]
Neuronal Mechanisms Govern Glioblastoma Cell Invasion
Xiaowu Lin1,2,3,4 · Zhihui Huang1,2,3,4 ·
Yongjie Wang1,2,3,4
2023,39(6):1027–1030 [
Abstract] [
SpringerLink]
[PDF]
Double-Edged Mossy Cells in Temporal Lobe Epilepsy: Evil in the Early Stage Through a BDNF-Dependent Strengthening Dentate Gyrus Circuit
Heming Cheng1
· Qiuwen Lou1
· Yi Wang1,2 ·
Zhong Chen1,3
2023,39(6):1031–1033 [
Abstract] [
SpringerLink]
[PDF]
One Small Step for Neurotechnology, One Giant Leap for an In-Depth Understanding of the Brain
Xiaoyun Qiu1
· Minjuan Sun1
· Cenglin Xu1
·
Yingying Tang2
· Zhong Chen1
2023,39(6):1034–1036 [
Abstract] [
SpringerLink]
[PDF]
Retraction Note to: Gray Matter-Based Age Prediction Characterizes Different Regional Patterns
Nianming Zuo1,2,3,4 · Tianyu Hu1,2,3 · Hao Liu1,2,3 · Jing Sui1,2,3,5 · Yong Liu1,2,3,5 · Tianzi Jiang1,2,3,4,5,6,7
2023,39(6):1037–1037 [
Abstract] [
SpringerLink]
[PDF]
The overexpression of transgenic mutant forms of APP/PS1 in 5XFAD mice results in early developmental defects of synaptic function, which could potentially contribute to age-dependent synaptic pathology and neurodegeneration later in life. As a result, while Alzheimer's disease is typically considered a condition that arises in old age, subtle neurological defects caused by genetic mutations or risk factors may emerge during the early stages of development. The cover illustrates the subtle neurological dysfunctions and defects in synaptic development in the 5XFAD mouse at an early post-weaning age, using a gray mouse cub in the lower left corner. These changes in neuronal function may initiate a lifelong process, depicted by the gray adult mouse in the lower right corner that cannot find its way back to its tree-hole home. See pages 881–892. (Cover provided by Chang Chen)