Generation of the Ci1 Reporter Mouse Strain with Enhanced Fluorescence for Tissue Clearing Applications
Manyu Chen1,3 · Youqi Li1,2,3 · Juan Huang3
·
Yilong Wang2,3 · Hu Zhao1,3
2025,41(8):1317–1328 [
Abstract] [
SpringerLink]
HOCPCA Exerts Neuroprotection on Retinal Ganglion Cells by Binding to CaMKIIα and Modulating Oxidative Stress and Neuroinflammation in Experimental Glaucoma
Panpan Li1,2 · Xin Shi1,3,4 · Hanhan Liu1
· Yuan Feng1
· Xiaosha Wang1
·
Marc Herb5,6 · Haichao Ji7
· Stefan Wagner7
· Johannes Vogt7
· Verena Prokosch1
2025,41(8):1329–1346 [
Abstract] [
SpringerLink]
Neural Dynamics of Visual Stream Interactions During Memory-Guided Actions Investigated by Intracranial EEG
Sofia Moraresku1,2 · Jiri Hammer3,4 · Vasileios Dimakopoulos5
·
Michaela Kajsova3,4 · Radek Janca4
· Petr Jezdik4
· Adam Kalina3,4 · Petr Marusic3,4 ·
Kamil Vlcek1,3,4
2025,41(8):1347–1363 [
Abstract] [
SpringerLink]
Brain White Matter Changes in Non-demented Individuals with Color Discrimination Deficits and Their Association with Cognitive Impairment: A NODDI Study
Jiejun Zhang1,2,3,5,6,7,8 · Peilin Huang1,5,6,7,8 · Lin Lin1,9 · Yingzhe Cheng1,5,6,7,8 · Weipin Weng1,5,6,7,8 ·
Jiahao Zheng1,5,6,7,8 · Yixin Sun1,5,6,7,8 · Shaofan Jiang4 · Xiaodong Pan1,5,6,7,8
2025,41(8):1364–1376 [
Abstract] [
SpringerLink]
GALM Alleviates Aβ Pathology and Cognitive Deficit Through Increasing ADAM10 Maturation in a Mouse Model of Alzheimer’s Disease
Na Tian1
· Junjie Li1
· Xiuyu Shi1
· Mingliang Xu1
· Qian Xiao1
· Qiuyun Tian1
·
Mulan Chen1
· Weihong Song2,3 · Yehong Du1
· Zhifang Dong1
2025,41(8):1377–1389 [
Abstract] [
SpringerLink]
Transcranial temporal interference stimulation precisely targets deep brain regions to regulate eye movements
Mo Wang1 · Sixian Song2,3 · Dan Li1
·
Guangchao Zhao4
· Yu Luo5
· Yi Tian2
· Jiajia Zhang2
·
Quanying Liu1 · Pengfei Wei2,3,5
2025,41(8):1390–1402 [
Abstract] [
SpringerLink]
Enhancement of Ca2+ Signal Strength in Astrocytes in the Lateral Septum Improves Cognitive Disorders in Mice After Hemorrhagic Shock and Resuscitation
Wen‑Guang Li1,2 · Lan‑Xin Li1
· Rong‑Xin Song3
· Xu‑Peng Wang4
· Shi‑Yan Jia1
·
Xiao‑Yi Ma1,5 · Jing‑Yu Zhang6
· Gang‑Feng Yin7
· Xiao‑Ming Li8
· Li‑Min Zhang1,3
2025,41(8):1403–1417 [
Abstract] [
SpringerLink]
The Role of Prefrontal and Posterior Parietal Cortex in Generating Multiple Step Saccades
Wenbo Ma1
· Zhaohuan Ding3
· Leixiao Feng2
·
Xiaoli Li4,5 · Mingsha Zhang2
2025,41(8):1418–1428 [
Abstract] [
SpringerLink]
Histopathological Insights into Demyelination and Remyelination After Spinal Cord Injury in Non-human Primates
Junhao Liu1,2 · Zucheng Huang1
· Kinon Chen4
· Rong Li1
· Zhiping Huang1
·
Junyu Lin1
· Hui Jiang1
· Jie Liu3
· Qingan Zhu1
2025,41(8):1429–1447 [
Abstract] [
SpringerLink]
The Dance Between Schwann Cells and Macrophages During the Repair of Peripheral Nerve Injury
Wei Li1
· Guixian Liu1
· Jie Liang1
· Xiao Wang1
· Meiying Song1
· Xiaoli Liu1
·
Luoyang Wang1
· Zijie Yang2
· Bei Zhang1
2025,41(8):1448–1462 [
Abstract] [
SpringerLink]
From Correlation to Causation: Understanding Episodic Memory Networks
Ahsan Khan1,4 · Jing Liu2
· Maité Crespo‑García3
· Kai Yuan4
· Cheng‑Peng Hu4
·
Ziyin Ren4
· Chun‑Hang Eden Ti4
· Desmond J. Oathes1
· Raymond Kai‑Yu Tong4
2025,41(8):1463–1486 [
Abstract] [
SpringerLink]
Interoceptive Dysfunction in Psychiatric Disorders and Non-invasive Neuromodulation for Improving Interoception
Huiru Cui1 · Jijun Wang1,2 · Chunbo Li1,3
2025,41(8):1487–1499 [
Abstract] [
SpringerLink]
The Eyes are The Windows To The Soul: Pupillary Changes Reflect The Consolidation of New and Old Memories During Sleep
Wei‑Kun Su1 · Yan‑Jia Luo2 · Fangyuan Li1 · Hong Jiang2 · Jing Wang1 ·
Ya‑Dong Li1,3
2025,41(8):1500–1502 [
Abstract] [
SpringerLink]
Threat-Driven Social Plasticity: Switch from Innate Attraction to Conditioned Preference
Hongyu Zuo1
· Jie Li1 · Xia Zhang1,2 · Bin Zhang1
2025,41(8):1503–1506 [
Abstract] [
SpringerLink]
GPR37L1 in Spinal Astrocytes: A Potential Target for Neuropathic Pain Management
Jingyang Xu1
· Yufeng Chen1
· Lerong Chen1,2 ·
Boyi Liu1,3
2025,41(8):1507–1510 [
Abstract] [
SpringerLink]
About the Cover
Traditional mouse reporters were not optimized for tissue clearing, leading to substantial fluorescence loss. Here, Chen et al. introduce the Ci1 reporter line, powered by the bright red fluorophore mScarlet and named after the Chinese Institute for Brain Research (CIBR). It outperforms the standard Ai14 reporter in every tested metric, most notably in signal retention after clearing. The creation of the Ci1 reporter provides a more effective tool for both neuroscience and other biomedical research applications. On the cover, a mouse relaxes under a green desk lamp, reading “How to Be a Superstar” and glowing red; CRISPR “bugs” in the background apply mouse-genetics cyclopedia, mScarlet wine, and “CRISPR chips” to rewrite its DNA strands. See pages 1317–1328. (Cover provided by Ms. Evelyn Xiaoya Zhao)
