Targeting Phospholipid Metabolism as an Effective Hearing Protection Strategy
Huanyu Mao1,2 · Wenli Ni1,2 · Lupeng Ma3
· Xiang Li1,2 · Yanping Zhang1,2 ·
Yuzheng Zhao5
· Wenyan Li1,2,4 · Huawei Li1,2,4 · Yan Chen1,2
2026,42(1):1–18 [
Abstract] [
SpringerLink]
From Brain to Shopping Cart: Neural Signals of Willingness to Buy Innovative Products
Ziyi Li1
· Lulu Liu1
· Ying Hu2
· Lushuang Zhang1
·
Xingxu Xie1
· Jing Luo1
2026,42(1):19–35 [
Abstract] [
SpringerLink]
Astrocyte-Derived CXCL10 Induces Neuronal Tau Hyperphosphorylation and Cognitive Impairments in Sepsis
Cuiping Guo1,2,3 · Hang Ruan1
· Wensheng Li3
· Yi Liu3
· Abdoul Razak Yacoubou Mahaman3
· Qian Guo3
·
You Zhou4
· Rong Liu3
· Jianzhi Wang3
· Chenliang Zhou4
· Xiaochuan Wang1,2,3,5 · Shusheng Li1
2026,42(1):36–54 [
Abstract] [
SpringerLink]
Temporal Variability Analysis of Cortical Blood Flow in Rats with Hyperacute Cerebral Ischemia
Bochao Niu1 · Benjamin Klugah‑Brown1 ·
Yang Xia1
· Dezhong Yao1 · Bharat B. Biswal1,2
2026,42(1):55–74 [
Abstract] [
SpringerLink]
Real-time Monitoring Unveils Three Distinct Neuronal Response Patterns to SAW Ultrasound via L-type Calcium Channels
Yiming Chen1 · Wenxu Tang2 · Yifan Wang1,3 · Ya Gao1,3 · Jiaqi Hu2,4 · Yixuan Lu2 · Long Meng5 ·
Hairong Zheng5 · Yi Feng6
· Liming Cheng3 · Wenyong Fan3 · Qian Cheng1,3,7 · Lei Xue2,8
2026,42(1):75–90 [
Abstract] [
SpringerLink]
Mapping the Cross-species Brain Connectivity Atlas and Hemispheric Asymmetry of the Temporal Pole in Humans and Macaques
Qinyao Sun1
· Shunli Zhu1
· Futing Yang2,3 · Zhigang Chen2,3 · Heling Li2,3 ·
Heng Shao4
· Hong Wang2,3 · Sangma Xie5
· Jiaojian Wang2,3
2026,42(1):91–106 [
Abstract] [
SpringerLink]
Temporal Features of Gamma Activity of Hyper-direct Pathway Regulated by Dopamine Receptors in the Dyskinetic Rat
Pengfei Wang1
· Weina Dai2
· Hongmin Li1
· Weijie Li1
· Yang Wang1
· Yichang Liu1
·
Le Wang1
· Fanglei Ye1
· Yuming Xu3,4
2026,42(1):107–126 [
Abstract] [
SpringerLink]
Tumor Necrosis Factor Alpha-Mediated Interaction Between Microglia and Müller Cells Exacerbates Retinal Ganglion Cell Damage in Experimental Glaucoma
Shu‑Ying Li1
· Hong Zhou1
· Guoli Zhao1,2 · Wen‑Wen Ding1
· Yu Zhang1
· Yong‑Chen Wang3
· Fang Li1
·
Yanying Miao1
· Xing‑Huai Sun1,2 · Zhongfeng Wang1
2026,42(1):127–152 [
Abstract] [
SpringerLink]
Complement C3a Suppresses Spinal Cord Neural Stem Cell Activation by Inhibiting UCHL1 via the NF-κB p65/Nrf2 Pathway
Lu Ding1
· Xinyue Li1
· YaQin Guo2
·
Feng‑Quan Zhou3 · David Y. B. Deng1
2026,42(1):153–174 [
Abstract] [
SpringerLink]
SHANK3 Deficiency in AgRP Neurons Inhibits Diet-Induced Obesity by Activating p38α
Shanshan Wu1,2,3,4 · Yixiao Liang1,2,3 · Yang Xu1,2,3 · Yueping Ge1,2,3 · Jing Wang1,2,3 · Lu Wang2
· Xinchen Jin5
·
Huidong Zhan1,2,3 · Li Peng1,2,3 · Ling Gao2
· Jiajun Zhao2
· Zhao He1,2,3
2026,42(1):175–188 [
Abstract] [
SpringerLink]
ADAM17 Supports Disinhibition of Pre-sympathetic Glutamatergic Neurons Through Microglial Chemotaxis
Jiawei Wang1
· Zihan Qiu1
· Yue Han1
· Hanxue Wu1
· Miao Yuan2
· Yan Liu1
· Huichao Wang1
· Shenglan Yuan1
·
Dengfeng Gao2
· Lina Sun3
· Xingjuan Chen4
· Eric Lazartigues5,6 · Fanni Li7
· Rui Yang1
· Jiaxi Xu1,2,8
2026,42(1):189–209 [
Abstract] [
SpringerLink]
Serotonergic Projection from the Dorsal Raphe Nucleus to the Basolateral Amygdala Bidirectionally Modulates Sociability in Mice
Yehui Zhang1
· Yuxiang Zhang1
· Yuwei Diao1
· Guangyi Yang1
· Guangrui Yang2
·
Xuchu Weng1
· Chun Hu1
2026,42(1):210–214 [
Abstract] [
SpringerLink]
Unveiling β Subunit-Dependent Gating Defects in CaV2.1 Channelopathies: Investigation of a de novo CACNA1A Variant
Kunpeng Ma1
· Haiyan Chen1,2 · Li Chen3
· Shuainan Zhao1
· Huafang Zou3
· Dongfang Zou3
· Qi Zeng3
·
Dezhi Cao3,4,5,6 · Jianyuan Sun1,5,6,7 · Lin Li4,6 · Xuefeng Shen1,5,6
2026,42(1):215–220 [
Abstract] [
SpringerLink]
Inner Ear Organoids: A Hydrogel-Based Platform for Drug Screening and Deafness Modeling
Yuyu Cao1
· Xiaotao Liu1
· Renjie Chai2 ·
Zuhong He1,3
2026,42(1):221–232 [
Abstract] [
SpringerLink]
Unveiling Butyrate as a Parkinson’s Disease Therapy
António E. Abreu1,2,3 · Nuno Empadinhas1,2 ·
Sandra Morais Cardoso1,2,3
2026,42(1):233–246 [
Abstract] [
SpringerLink]
Neural-Activity-Regulated Development of Meningeal Lymphatic System in Zebrafish: Novel Mechanism of Brain Self-Cleaning and Neuroimmune Regulation
Guangdong Liu1
· Weidong Le1
2026,42(1):247–250 [
Abstract] [
SpringerLink]
Dual Transmitter Oscillations for Ejaculation
Anqi Wei1
· Shuqin Zhan1
· Hong Fan1
·
Huadong Xu1 · Xinjiang Kang2,3 ·
Changhe Wang1,2,3
2026,42(1):251–253 [
Abstract] [
SpringerLink]
About the Cover
Sensorineural hearing loss is a widespread and debilitating condition with limited therapeutic drugs. In this issue, Mao et al. demonstrate that arginine supplementation enhances membrane phospholipid saturation through the Lands cycle and protects cochlear hair cells from phospholipid peroxidation-induced membrane damage and subsequent cell death. The cover draws inspiration from the classic Chinese tale Journey to the West (西游记), where Guanyin (观音, the Goddess of Mercy) revives the ginseng fruit tree with her sacred nectar. In this modern reinterpretation, Guanyin is sprinkling "nectar" containing arginine, a powerful therapeutic molecule, onto a tree bearing ear-shaped fruits. The ear-shaped fruits symbolize cochlear hair cells, which are essential for hearing, while the arginine-infused “nectar” represents their remarkable ability to protect and restore these delicate cells. The imagery beautifully conveys the idea that arginine, much like the life-giving nectar in the story, holds the potential to heal and preserve hearing function. See pages 1–18. (Cover provided by Huanyu Mao).
