Precise Magnetic Stimulation of the Paraventricular Nucleus Improves Sociability in a Mouse Model of ASD
Sha Liu1,2 · Quyang Yang1,2 · Pengfei Zhu1,2 · Xuan Liu3
· Qingbo Lu4
· Jie Yang7
·
Jingyao Gao7
· Hongbin Han8
· Zhijun Zhang4,6 · Ning Gu5
· Tao Tan7
· Jianfei Sun1,2
2025,41(10):1711–1728 [
Abstract] [
SpringerLink]
The Glutamate-gated Chloride Channel Facilitates Sleep by Enhancing the Excitability of Two Pairs of Neurons in the Ventral Nerve Cord of Drosophila
Yaqian Fan1 · Yao Tian1 · Junhai Han1,2
2025,41(10):1729–1742 [
Abstract] [
SpringerLink]
Comprehensive Brain-wide Mapping of Afferent and Efferent Nuclei Associated with the Heart in the Mouse
Haiying Liu1
· Xin Huang1
· Ruixin Xia1
· Xin Zhao1
· Zimeng Li1
· Qian Liu1
·
Congye Li2
· Honghui Mao1
· Wenting Wang1 · Shengxi Wu1
2025,41(10):1743–1760 [
Abstract] [
SpringerLink]
OGT-Mediated O-GlcNAcylation of ATF2 Protects Against Sepsis-Associated Encephalopathy by Inhibiting Microglial Pyroptosis
Huan Yao1,2 · Caixia Liang1
· Xueting Wang1,3 · Chengwei Duan1
· Xiao Song4
·
Yanxing Shang1
· Mingyang Zhang1,2 · Yiyun Peng1,2 · Dongmei Zhang1,2
2025,41(10):1761–1778 [
Abstract] [
SpringerLink]
Neural Responses to Hypoxic Injury in a Vascularized Cerebral Organoid Model
Yang Li1
· Xin‑Yao Sun1,2 · Peng‑Ming Zeng1
·
Zhen‑Ge Luo1
2025,41(10):1779–1791 [
Abstract] [
SpringerLink]
In Vitro and Animal Studies of Human Natural Killer Cell-Derived Exosomes for the Treatment of Otitis Media
Zirui Zhao1,2 · Liqin Wang1,2 · Zhen Guo3
· Kanglun Jiang4
· Jianghong Xu1,2 · Yilai Shu1,2 · Christina Y. Xu5
·
Jianning Zhang6 · Yunfeng Wang1,2 · Geng‑Lin Li1,2
2025,41(10):1792–1804 [
Abstract] [
SpringerLink]
USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation
Juan Yang1,2 · Haiqing Zhang2
· You Wang1
· Yuemei Luo2
· Weijin Zheng3
· Yong Liu1
· Qian Jiang1
· Jing Deng1,4 ·
Qiankun Liu1
· Peng Zhang1
· Hao Huang2
· Changyin Yu2 · Zucai Xu2 · Yangmei Chen1
2025,41(10):1805–1823 [
Abstract] [
SpringerLink]
Parvalbumin and Somatostatin Neurons in the Thalamic Reticular Nucleus Modulate Visual Information Processing in V1 of Mouse
Jiamin Bu1
· Guangwei Xu1
· Yifeng Zhou1,2
2025,41(10):1824–1842 [
Abstract] [
SpringerLink]
Combined Study of Behavior and Spike Discharges Associated with Negative Emotions in Mice
Jinru Xin1
· Xinmiao Wang1,2 · Xuechun Meng1
· Ling Liu1
· Mingqing Liu1
·
Huangrui Xiong1
· Aiping Liu1 · Ji Liu1,3,4
2025,41(10):1843–1860 [
Abstract] [
SpringerLink]
Single-Nucleus RNA-Seq Reveals PTSD-Associated Transcriptional Changes in Dopaminergic Neurons of the Lateral VTA
Peiling Zhou1
· Hongwei Yan1
· Jingtong Wu1
· Qinghui Lan1
· Xue‑Min Wang2
·
Jin‑Jun Ding3
· Hai‑Tao Wu4
· Changzheng Zhang1
2025,41(10):1861–1866 [
Abstract] [
SpringerLink]
Bridging the Gap: The Neuro-immune Axis as a Key Player in Neurodegenerative Disorders
Tingting Liu1
· Haojie Wu1
· Jianshe Wei1
2025,41(10):1867–1887 [
Abstract] [
SpringerLink]
Liquid–Liquid Phase Separation in Hereditary Hearing Loss
Kefan Tao1
· Yanjun Zong1
· Xiaozhou Liu1
·
Xinyu Shi1
· Zhengdong Zhao1
· Yu Sun1,2,3
2025,41(10):1888–1900 [
Abstract] [
SpringerLink]
Into the Spotlight: Microglia in the Peripheral Nervous System
Ruichao E. Liu1,2,3 · Coco Chu1,2,3,4,5,6 · Hai Qi1,2,3,4,5,7,8,9
2025,41(10):1901–1904 [
Abstract] [
SpringerLink]
TRAILblazing Astrocytes: Glioblastoma’s Covert Immunosuppressive Agents
Jia‑Qi Zhang1 · Wei Sun2,3 · Wei‑Lin Jin4
2025,41(10):1905–1908 [
Abstract] [
SpringerLink]
About the Cover
Conventional magnetic stimulation techniques are limited in their precision for targeting deep brain nuclei such as the paraventricular nucleus (PVN). Liu et al. introduce a nanoparticle-mediated precise magnetic stimulation (pMSS) technique that enables accurate modulation of neuronal activity in the PVN. In a mouse model of autism spectrum disorder, application of 10-Hz pMSS stimulated endogenous oxytocin release, enhanced neurite outgrowth, and ameliorated social deficits—offering a novel therapeutic strategy for disorders involving social dysfunction. On the cover, the deconstructed totem of Nüwa represents the hypothalamic–pituitary neuroaxis, with golden neural pathways converging into an oxytocin molecule cradled in her palm. The radiating indigo magnetic waves reflect the field distribution model of deep brain stimulation, transforming the ancient goddess’s gesture of mending the heavens into a visual metaphor for contemporary magnetic neuromodulation technologies. See pages 1711–1728. (Cover provided by Sha Liu)
