Volume 40, Issue 4, April, 2024

Original Articles

Inflammatory Factor IL1α Induces Aberrant Astrocyte Proliferation in Spinal Cord Injury Through the Grin2c/Ca2+/CaMK2b Pathway
Yu Xia1 · Lu Ding1 · Changlin Zhang2,3 · Qi Xu1 · Ming Shi1 · Tianshun Gao4 · Feng‑Quan Zhou5 · David Y. B. Deng1,6
2024,40(4):421–438   [ Abstract]   [ SpringerLink]

Developmental Impairments of Synaptic Refinement in the Thalamus of a Mouse Model of Fragile X Syndrome
Xiaotong Wu1,2,3 · Yali Liu1,3 · Xiaomeng Wang1,2,3 · Lu Zheng1,3 · Libiao Pan1,3 · Hao Wang1,2,3,4
2024,40(4):439–450   [ Abstract]   [ SpringerLink]

GM-CSF Promotes the Development of Dysfunctional Vascular Networks in Moyamoya Disease
Huiqin Li1 · Xiang Cao1,2,4,5,6,7 · Xinya Gu3 · Mengqi Dong4 · Lili Huang1 · Chenglu Mao1 · Shengnan Xia1 · Haiyan Yang1 · Xinyu Bao1 · Yongbo Yang1 · Yun Xu1,2,3,4,5,6,7
2024,40(4):451–465   [ Abstract]   [ SpringerLink]

Tau Accumulation in the Spinal Cord Contributes to Chronic Inflammatory Pain by Upregulation of IL-1β and BDNF
Shuxia Zhang1 · Yeru Chen1 · Yongjie Wang2,3 · Hongwei Wang1 · Dandan Yao1 · Gang Chen1
2024,40(4):466–482   [ Abstract]   [ SpringerLink]

MFG-E8 Alleviates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Phagocytosing Myelin Debris and Promoting Remyelination
Xiaohong Dong1,2 · Zhi Zhang1,2 · Xin Shu1,2 · Zi Zhuang3 · Pinyi Liu1,4,5 · Renyuan Liu1,4,5 · Shengnan Xia1,4,5 · Xinyu Bao1,4,5 · Yun Xu1,2,3,4,5 · Yan Chen1,4,5
2024,40(4):483–499   [ Abstract]   [ SpringerLink]


Relationship Between Short-chain Fatty Acids and Parkinson’s Disease: A Review from Pathology to Clinic
Wen‑Xiang Duan1 · Fen Wang1,3 · Jun‑Yi Liu2 · Chun‑Feng Liu1,3
2024,40(4):500–516   [ Abstract]   [ SpringerLink]

Multimodal Nature of the Single-cell Primate Brain Atlas: Morphology, Transcriptome, Electrophysiology, and Connectivity
Yuhui Shen1 · Mingting Shao1 · Zhao‑Zhe Hao1 · Mengyao Huang1 · Nana Xu1 · Sheng Liu1,2
2024,40(4):517–532   [ Abstract]   [ SpringerLink]

Letters to the Editor

Disease Burden and Costs Associated with Multiple Sclerosis in China: A Cross-sectional Analysis of Nationwide Survey Data
Yusheng Jia1 · Xuanqi Qiao1 · Jin Zhao1 · Hainan Li1 · Shanlian Hu1 · Min Hu1,2
2024,40(4):533–538   [ Abstract]   [ SpringerLink]

Knockdown of SIRT2 Rescues YARS-induced Charcot-Marie-Tooth Neuropathy in Drosophila
Xuedong Li1,2 · Mengrong Wang1 · Xiang Gao3 · Chenyu Li1 · Chunyu Chen1 · Yun Qi1 · Ying Wan2 · Wei Yu1
2024,40(4):539–543   [ Abstract]   [ SpringerLink]

Research Highlights

Neural Circuitry Involving Substance P in Male Sexual Behavior
Xinrong Wang1,2 · Junqiang Zheng1,5 · Han Xu1,2,3,4,5
2024,40(4):544–546   [ Abstract]   [ SpringerLink]

Functional Changes in Astrocytes Lead to Cognitive Deficits After Social Deprivation
Yulan Li1 · Lixuan Li2 · Yibei Wang1 · Yi Wang1 · Zhong Chen1,2
2024,40(4):547–549   [ Abstract]   [ SpringerLink]

LH-Nts Neurons Regulate VTA Calcium Dynamics Via Releasing GABA and Nts
Danni Chen1,2 · Yinfeng Yuan1,2 · Zhihui Huang1,2 · Yongjie Wang1,2
2024,40(4):550–552   [ Abstract]   [ SpringerLink]


Microglial Calcium Homeostasis Modulator 2: Novel Anti-neuroinflammation Target for the Treatment of Neurodegenerative Diseases
Yuan Dong1 · Li Tang2
2024,40(4):553–556   [ Abstract]   [ SpringerLink]

Can NogoA Be a Suitable Target to Treat Ischemic Stroke?
Suliman Khan1 · Abdul Nasir1
2024,40(4):557–560   [ Abstract]   [ SpringerLink]

Volume 40, Issue 4, April, 2024

About the Cover

In recent years, it has been recognized that the brain-gut-microbiota axis is closely linked to the pathogenesis of Parkinson's disease (PD). Duan et al. review the role of the most important microbial metabolites, short-chain fatty acids (SCFAs), in PD, and highlight its potential therapeutic value. The cover image graphically illustrates the importance of gut health and SCFAs balance in PD, with the PD patient on the right walking on a diseased gut, stumbling unaided. The brain is also traumatized and emits a dark light. On the contrary, the PD patient on the left stands on a normal intestinal tract, happily practicing Tai Chi. The brain radiates light with a less pathological burden as a result. See pages 500–516. (Cover designed by Wenxiang Duan and Junyi Liu).