Current Issue Table of Contents: 15 March, 2026, Volume 42, Issue 3
About the Cover
In this issue, Wang et al. mapped cortical layer 2/3 neuronal activity across transitions between states of consciousness. Combining high-resolution wide-field calcium imaging with unbiased segmentation of population dynamics and activity-feature clustering, they show that neuronal roles are state-dependent and that neurons within the same functional group can be reassigned and switch roles across stages. The cover centers on a stylized “neural tree” to symbolize single-neuron information reception and integration. Its axon is rendered as a multicolored flowing stream, representing the activity trajectories and identity shifts of different functional groups across phases. The layered foliage in the background evokes the vastness of cortical networks and the mystery of consciousness, underscoring the limitations of our understanding of consciousness mechanisms; we “can’t see the forest for the trees”. See pages 491–504. (Cover designed by Zilin Wang)
Call for Papers: Special Issue on Zebrafish Models in Neuroscience Research
Guest Editor: Prof. Alan V. Kaluev
Special Issue Celebrating the 25th Anniversary of the Institute of Neuroscience, CAS
Ting Lv1 · Yefei Li1 · Fei Dong1 · Shumin Duan2
Cenglin Xu1 · Yi Wang1 · Zhong Chen1
Correction to: Long-Term Monochromatic Light Exposure Does Not Alter Modular Chromatic Representation in the Visual Cortex of Rhesus Monkeys
Wenqing Zhu1,3,4 · Ye Liu2 · Xiaoxiao Chen1,3,4 · Liling Qian2
· Wei Wang2,6 ·
Leilei Zou5
· Yiliang Lu2 · Rui Liu1,3,4
[SpringerLink]
Acoustic Flutter Processing in the Inferior Colliculus of Awake Marmosets: Complementary Rate Coding Modulated by Acoustic Parameters
Siyi Bai1,4 · Xinyuan Cao1
· Min Xie1
· Guanglong Sun1
·
Xiaohui Wang1,4 · Leilei Zheng1
· Xinjian Li1,3 ·
Zheng Lin1
· Lixia Gao1,2,3,4
[SpringerLink]
Microglia Pyroptosis-Derived IL-18 Drives White Matter Injury in Developing Brain following Hypothermic Hypoxia-Ischemia
Hongtong Chen1
· Shengyu Jin2,3,4 · Mingdong Liu3,5 ·
Yifan Zhu1
· Liren Zhang6
· Cong Li1
· Peng Liu4
·
Xiaoping Tong2,3,4 · Zhongqun Zhu1
[SpringerLink]
Tissue-Resident Macrophage PIEZO1 Transduces Mechanical Stress into Inflammatory Pain in Acute Gout
Tianyi Shen1,2 · Ting Wang1,2 · Liyan Wu1,2 · Zihan Wang1,2 · Liqin Gan3
· Yubin Luo4
· Cong Liu5
·
Yang Xu6
· De‑An Guo2,3 · Qirui Bi3
· Wanying Wu2,3 · Lvyi Chen7
· Yi Chang8
· Jing Feng1,2
[SpringerLink]
Ca2+-Independent Exocytosis Favors Axonal Release through Enlarged Fusion Pores in Sensory Neurons
Rong Huang1,2 · Xingyu Du1
· Qihui Wu1,3 · Yuan Wang1
· Yuqi Hang1
· Xi Wu1
· Yiman Li1
· Jie Li1
·
Zhongjun Qiao1
· Yinglin Li1
· Lili Yin1
· Xiaoxuan Sun1
· Bing Liu1
· Feipeng Zhu1
· Quanfeng Zhang1
·
Changhe Wang2,4 · Zuying Chai1,5 · Zhuan Zhou1
[SpringerLink]
Endoplasmic Reticulum Stress in the Keratinocytes Contributes to Chronic Itch by Activation of Lipocalin 2/MC4R/TRPV1 Pathway
Wei Ge1,2 · Yu Feng3
· Li Zhang4
· Qian‑Liang Wang1
· Cheng‑Wei Zhang5
· Zhi‑Hong Wang6
· Guo‑Kun Zhou7
·
Shi‑Yu Sun7
· Xiu‑Hua Miao8
· Tong Liu7 · Bin Wu9 · Jun Yan1
[SpringerLink]
Beyond the Wiring: White Matter as a Dynamic Regulator of Brain Function and Disease
Chenzhao He1
· Debao Wu1
· Ailian Du1
·
Liang Zhang1,2
[SpringerLink]
Aging-Related Changes in the Injury Response of the Peripheral Nervous System
Yue‑Yan Cen1,2 · Mu‑Yun Wang1,2 · Qin‑Xuan Song1,2 ·
Xin‑Lin Gao1,2 · Cheng Zhou3
· Chun‑Jie Li1,4 ·
Fei Liu1,2 · Yan‑Yan Zhang1,2 · Jie‑Fei Shen1,2
[SpringerLink]
A New Driver of Parkinson’s Disease: FAM171A2 Facilitates α-Synuclein Uptake and Spread
Qiuhan Wang1 · Tao Qiu1 · Yiying Hu1,2 ·
Tianbai Li1
[SpringerLink]
Synaptic Protein Lactylation: A Novel Mechanism Underlying Physical Exercise-mediated Stress Resilience
Can‑Yuan Zhang1 · Su‑Fen Wei1,2 · Xiong Cao1
[SpringerLink]
The Eyes are The Windows To The Soul: Pupillary Changes Reflect The Consolidation of New and Old Memories During Sleep
Wei‑Kun Su1 · Yan‑Jia Luo2 · Fangyuan Li1 · Hong Jiang2 · Jing Wang1 ·
Ya‑Dong Li1,3
[SpringerLink]
Threat-Driven Social Plasticity: Switch from Innate Attraction to Conditioned Preference
Hongyu Zuo1
· Jie Li1 · Xia Zhang1,2 · Bin Zhang1
[SpringerLink]
GPR37L1 in Spinal Astrocytes: A Potential Target for Neuropathic Pain Management
Jingyang Xu1
· Yufeng Chen1
· Lerong Chen1,2 ·
Boyi Liu1,3
[SpringerLink]
Imaging and Quantifying the Diversity of Native NMDA Receptors
Sophie Shi1 · David Stroebel1 · Laetitia Mony1 ·
Pierre Paoletti1
[SpringerLink]
Novel Strategies for Cognitive Enhancement via Noninvasive Neuromodulation
Hongwei Li1,2 · Kun Zhao2,3 · Yong Liu2,3,4
[SpringerLink]
The Astrocyte: A New Component of The Engram Regulates Memory Recall
Ru Li1,2 · Zilan Luo1,2 · Ding Zhong2,4 · Xia Deng2
·
Liang Gao1,2,3
[SpringerLink]
Cortical Dysplasia Beyond mTOR: Cellular Senescence Takes a Toll
Yixin Zhan1,2 · Jiping Zhou3 · Guoqing Zheng1,2 ·
Yang Zheng1,2
[SpringerLink]
Zona Incerta: A Bridge for Infant-Mother Interaction
Yawen Huang1
· Jun Wang2,3,4,5 · Na Liu2,3,4,5 ·
Han Xu2,3,4,5
[SpringerLink]
Mapping Fear-Related Neural Activity and Circuitry Changes Following Prophylactic Administration of (R,S)-Ketamine and (2S,6S)-Hydroxynorketamine
Minzhu Li1
· Li Cheng1
[SpringerLink]
“CATCH ME IF YOU CAN”: Unlocking the Hidden Key in Obesity Intervention via the Vagus-Jejunum Axis
Shuo Zhang1,2 · Lingyu Xu1
· Yila Ding1
· Cenglin Xu1
[SpringerLink]
Psilocybin and Obsessive-Compulsive Disorder: Exploring New Therapeutic Horizons
Longwei Yang1,2 · Haohong Li3,4 · Xiaohui Wang1,2,4
[SpringerLink]
Exploring the Therapeutic Potential of Psychedelics in Chronic Pain Management: A New Frontier in Medicine
Cong Lin1
· Xue Wang2
· Xiaohui Wang1,3
[SpringerLink]
Halting the Progression of Alzheimer’s Disease: Is the Goal in Sight?
Yu‑Juan Jia1,2 · Xuan‑Yue Wang3
· Jie Liu2
· Yan‑Jiang Wang4,5 ·
Colin L. Masters6 · Jun‑Hong Guo1
[SpringerLink]
The Current State and Future Outlook of PET Tracers for AMPA Receptors
Ling Li1
· Shenglin Wen1
· Ji Dai2,3,4,5
[SpringerLink]
Psychoactive Substances: Transforming the Paradigm for Treating Mental Health Disorders in the Post-Pandemic Era
Haojiang Zhai1,2 · Yibo Wang1 · Xiaohui Wang1,2
[SpringerLink]
Neurotensin Modulates Emotional Valence Assignment in the Basolateral Amygdala Through Neuromodulator Gain
Maimaitishalijiang Abudureheman1,2 · Yu‑Hao Xiao1,2 ·
Li‑Zang Zeng1,2 · Hong‑Yan Geng1,2
[SpringerLink]
Constructing A Theoretical Model to Bridge Neural Transition with a State Switch in Bipolar Disorder
Xiaonan Guo1
· Lizichen Chen2
· Jianbo Lai1,4 ·
Shaohua Hu1,3,4,5,6,7,8
[SpringerLink]
Liquid–Liquid Phase Separation within Dense-Core Vesicles in Sympathetic Adrenal Chromaffin Cells
Quanfeng Zhang1
· Zhaohan Lin1
· Xinyu Du1
·
Zhuan Zhou1,2,3
[SpringerLink]
The Claustrum Controls Motor Activity Through Anterior Cingulate Cortex Input and Local Circuit Synchronization in a Preparatory Manner
Zi‑Qi Kou1,2 · Chun‑Yan Chen1,2 · Mamatsali Abdurahman1,2 · Xu‑Chu Weng1,2 ·
Chun Hu1,2 · Hong‑Yan Geng1,2
[SpringerLink]
Photobiomodulation: A Potential Non-invasive Method to Alleviate Neurological Events Following COVID-19 Infection
Chongyun Wu1
· Timon Cheng‑Yi Liu1
· Rui Duan1
·
Luodan Yang1
[SpringerLink]
The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals
Yuncheng Zhu • Liangliang Chen • Haifeng Ji • Maomao Xi • Yiru Fang • Yi Li
[SpringerLink]
Expert Consensus on the Care and Management of Patients with Cognitive Impairment in China
Academy of Cognitive Disorders of China (ACDC) • Yuliang Han • Jianjun Jia • Xia Li • Yang Lv • Xuan Sun • Shanshan Wang • Yongjun Wang • Zhiwen Wang • Jintao Zhang • Jiong Zhou & Yuying Zhou
[SpringerLink]
An Overview of the Expert Consensus on the Prevention and Treatment of Gaming Disorder in China (2019 Edition)
Yu-Tao Xiang • Yu Jin • Ling Zhang • Lu Li • Gabor S. Ungvari • Chee H. Ng • Min Zhao & Wei Hao
[SpringerLink]
Perspective on Etiology and Treatment of Bipolar Disorders in China: Clinical Implications and Future Directions
Zuowei Wang • Chen Jun • Keming Gao • Haichen Yang • Yiru Fang
[SpringerLink]
Standardized Operational Protocol for Human Brain Banking in China
Wenying Qiu • Hanlin Zhang • Aimin Bao • Keqing Zhu • Yue Huang • Xiaoxin Yan • Jing Zhang • Chunjiu Zhong • Yong Shen • Jiangning Zhou • Xiaoying Zheng • Liwei Zhang • Yousheng Shu • Beisha Tang • Zhenxin Zhang • Gang Wang • Ren Zhou • Bing Sun • Changlin Gong • Shumin Duan & Chao Ma
[SpringerLink]
Oxidative stress in Alzheimer's disease
Zhichun Chen, Chunjiu Zhong
[SpringerLink]
Emerging role of Toll-like receptors in the control of pain and itch
Tong Liu, Yong-Jing Gao and Ru-Rong Ji
[SpringerLink]
An Overview of Autism Spectrum Disorder, Heterogeneity and Treatment Options OPEN ACCESS
Anne Masi • Marilena M. DeMayo • Nicholas Glozier • Adam J. Guastella
[SpringerLink]
Caspase-3 activation as a bifurcation point between plasticity and cell death
Shikha Snigdha, Erica D Smith, G Aleph Prieto, Carl W Cotman
[SpringerLink]
Behavioral animal models of depression
Hua-Cheng YAN, Xiong CAO, Manas Das, Xin-Hong ZHU, Tian-Ming GAO
[SpringerLink]
The glial scar in spinal cord injury and repair
Yi-Min Yuan, Cheng He
[SpringerLink]
Roles of the hippocampal formation in pain information processing
Ming-Gang LIU, Jun CHEN
[SpringerLink]
Impaired Hypothalamic Regulation of Sympathetic Outflow in Primary Hypertension
Jing-Jing Zhou • Hui-Jie Ma • Jian-Ying Shao • Hui-Lin Pan • De-Pei Li
[SpringerLink]
The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals
Yuncheng Zhu 1 • Liangliang Chen 2 • Haifeng Ji 2 • Maomao Xi 3 • Yiru Fang 1,5,6 • Yi Li 4
[SpringerLink]
An Overview of Autism Spectrum Disorder, Heterogeneity and Treatment Options OPEN ACCESS
Anne Masi1 • Marilena M. DeMayo1 • Nicholas Glozier1 • Adam J. Guastella1
[SpringerLink]
Pharmacological Modulation of Vagal Nerve Activity in Cardiovascular Diseases
Longzhu Liu • Ming Zhao • Xiaojiang Yu • Weijin Zang*
[SpringerLink]
Gene Editing to the Rescue: Reversal of Social Deficits Associated with MECP2 Duplication
Zi-Xian Yu 1,2,3 • Dan-Yang Wang 1,2,3 • Xiao-Hong Xu 1,3
[SpringerLink]
Regulation of Pain and Itch by TRP Channels
Carlene Moore1 • Rupali Gupta1 • Sven-Eric Jordt2 • Yong Chen1,* • Wolfgang B. Liedtke1,2,*
[SpringerLink]
Spinal Circuits Transmitting Mechanical Pain and Itch
Bo Duan1,* • Longzhen Cheng2,* • Qiufu Ma3,*
[SpringerLink]
Special Issue on Pain and Itch
Issue Editor: Ru-Rong Ji
2025 Vol 41 Issue 12
[PDF]
[SpringerLink]
Special Issue Celebrating the 25th Anniversary of the Institute of Neuroscience, CAS
Issue Editors: ting lv,Fei Dong,Shumin Duan,Yefei Li
2024 Vol 40 Issue 11
[PDF]
[SpringerLink]
Special Issue on Novel Mechanism, Drug Target and Therapy in Epilepsy
Issue Editor: Zhong Chen
2024 Vol 40 Issue 5
[PDF]
[SpringerLink]
Special Issue on Novel Insight into Glial Biology and Diseases
Issue editor: He Cheng
2023 Vol 39 Issue 3
[PDF]
[SpringerLink]
Special Issue on Pain and Itch
Guest Editor: Ru-Rong Ji
2022 Vol 38 Issue 4
[PDF]
[SpringerLink]